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Cellosaurus RCC-1 clone 2F5 (CVCL_D2QQ)

[Text version]
Cell line name RCC-1 clone 2F5
Synonyms RCC-1(2F5)
Accession CVCL_D2QQ
Resource Identification Initiative To cite this cell line use: RCC-1 clone 2F5 (RRID:CVCL_D2QQ)
Comments Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11735.
Population: African; Nigerian.
Virology: Infected with human herpesvirus 8 (HHV-8/KSHV). Produced by the co-cultivation of Raji cells with BC-1 cells (Cellosaurus=CVCL_1079) separated by filter tissue culture inserts to prevent cross-contamination (from parent cell line).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D2QP (RCC-1)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Publications

Patent=US5849564
Chang Y., Bohenzky R.A., Russo J.J., Edelman I.S., Moore P.S.
Polypeptides from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof.
Patent number US5849564, 15-Dec-1998

Patent=US5861500
Chang Y., Bohenzky R.A., Russo J.J., Edelman I.S., Moore P.S.
Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin 6 (IL-6) and uses thereof.
Patent number US5861500, 19-Jan-1999

Cross-references
Encyclopedic resources Wikidata; Q127384027
Entry history
Entry creation30-Jan-2024
Last entry update19-Dec-2024
Version number4