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Cellosaurus MZ2-MEL.3.1 (CVCL_C5U7)

[Text version]
Cell line name MZ2-MEL.3.1
Synonyms MZ2-Mel 3.1
Accession CVCL_C5U7
Resource Identification Initiative To cite this cell line use: MZ2-MEL.3.1 (RRID:CVCL_C5U7)
Comments Population: Caucasian.
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser257Leu (c.770C>T); ClinVar=VCV000013957; Zygosity=Heterozygous (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C5U4 (MZ2-MEL.3.0)
Children:
CVCL_C5VC (MZ2-MEL.2.2)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2529220; DOI=10.1002/ijc.2910440413
van den Eynde B.J., Hainaut P., Herin M., Knuth A., Lemoine C., Weynants P., van der Bruggen P., Fauchet R., Boon T.
Presence on a human melanoma of multiple antigens recognized by autologous CTL.
Int. J. Cancer 44:634-640(1989)

PubMed=8566071; DOI=10.1002/eji.1830260135
Brichard V.G., Herman J., Van Pel A., Wildmann C., Gaugler B., Wolfel T., Boon T., Lethe B.
A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes.
Eur. J. Immunol. 26:224-230(1996)

Cross-references
Encyclopedic resources Wikidata; Q116049845
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number4