| Cell line name |
MZ2-MEL.3.0 |
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| Synonyms |
MZ2-MEL clone 3.0 |
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| Accession |
CVCL_C5U4 |
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| Resource Identification Initiative |
To cite this cell line use: MZ2-MEL.3.0 (RRID:CVCL_C5U4) |
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| Comments |
Population: Caucasian.
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916. |
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| Sequence variations |
- Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser257Leu (c.770C>T); ClinVar=VCV000013957; Zygosity=Heterozygous (from parent cell line).
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| Disease |
Melanoma (NCIt: C3224) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1435 (MZ-MEL-2)
Children:
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| Sex of cell |
Sex unspecified |
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| Age at sampling |
Age unspecified |
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| Category |
Cancer cell line |
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| Publications | PubMed=2529220; DOI=10.1002/ijc.2910440413
van den Eynde B.J., Hainaut P., Herin M., Knuth A., Lemoine C., Weynants P., van der Bruggen P., Fauchet R., Boon T.
Presence on a human melanoma of multiple antigens recognized by autologous CTL.
Int. J. Cancer 44:634-640(1989) PubMed=8509230; DOI=10.1002/ijc.2910540329
Rimoldi D., Romero P., Carrel S.
The human melanoma antigen-encoding gene, MAGE-1, is expressed by other tumour cells of neuroectodermal origin such as glioblastomas and neuroblastomas.
Int. J. Cancer 54:527-528(1993) PubMed=8566071; DOI=10.1002/eji.1830260135
Brichard V.G., Herman J., Van Pel A., Wildmann C., Gaugler B., Wolfel T., Boon T., Lethe B.
A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes.
Eur. J. Immunol. 26:224-230(1996) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q116049844
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| Entry history |
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| Entry creation | 15-Dec-2022 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 4 |
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