| Cell line name |
MZ2-MEL.2.2 |
|---|
| Synonyms |
MZ2-Mel 2.2; MZ2-MEL clone 2.2 |
|---|
| Accession |
CVCL_C5VC |
|---|
| Resource Identification Initiative |
To cite this cell line use: MZ2-MEL.2.2 (RRID:CVCL_C5VC) |
|---|
| Comments |
Population: Caucasian.
Derived from site: Metastatic; Abdomen; UBERON=UBERON_0000916. |
|---|
| Sequence variations |
- Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9829; RAF1; Simple; p.Ser257Leu (c.770C>T); ClinVar=VCV000013957; Zygosity=Heterozygous (from parent cell line).
|
|---|
| Disease |
Melanoma (NCIt: C3224) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_C5U7 (MZ2-MEL.3.1) |
|---|
| Sex of cell |
Sex unspecified |
|---|
| Age at sampling |
Age unspecified |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=2529220; DOI=10.1002/ijc.2910440413
van den Eynde B.J., Hainaut P., Herin M., Knuth A., Lemoine C., Weynants P., van der Bruggen P., Fauchet R., Boon T.
Presence on a human melanoma of multiple antigens recognized by autologous CTL.
Int. J. Cancer 44:634-640(1989) PubMed=8509230; DOI=10.1002/ijc.2910540329
Rimoldi D., Romero P., Carrel S.
The human melanoma antigen-encoding gene, MAGE-1, is expressed by other tumour cells of neuroectodermal origin such as glioblastomas and neuroblastomas.
Int. J. Cancer 54:527-528(1993) PubMed=8566071; DOI=10.1002/eji.1830260135
Brichard V.G., Herman J., Van Pel A., Wildmann C., Gaugler B., Wolfel T., Boon T., Lethe B.
A tyrosinase nonapeptide presented by HLA-B44 is recognized on a human melanoma by autologous cytolytic T lymphocytes.
Eur. J. Immunol. 26:224-230(1996) |
|---|
| Cross-references |
|---|
| Encyclopedic resources |
Wikidata; Q116049843
|
|---|
| Entry history |
|---|
| Entry creation | 15-Dec-2022 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 4 |
|---|
