Cellosaurus VeroE6-Pgp-KO (CVCL_C4RQ)
| Cell line name | VeroE6-Pgp-KO |
|---|---|
| Accession | CVCL_C4RQ |
| Resource Identification Initiative | To cite this cell line use: VeroE6-Pgp-KO (RRID:CVCL_C4RQ) |
| Comments | Group: Non-human primate cell line. Group: SARS-CoV-2 research cell line. Virology: Can be used for in vitro virus infection system for SARS-CoV-2 and possibly other viruses to test antiviral therapies without a need to control the ABCB1/Pgp efflux transporter activity (PubMed=36208677). Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9RIY5; ABCB1. Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819. Cell type: Epithelial cell of kidney; CL=CL_0002518. |
| Species of origin | Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711) |
| Hierarchy | Parent: CVCL_0574 (Vero C1008) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=36208677; DOI=10.1016/j.antiviral.2022.105429; PMCID=PMC9533647 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q116050765 |
| Entry history | |
| Entry creation | 15-Dec-2022 |
| Last entry update | 05-Oct-2023 |
| Version number | 4 |