Cellosaurus logo
expasy logo

Cellosaurus A549 EGFR Knockout (CVCL_C3DB)

[Text version]
Cell line name A549 EGFR Knockout
Synonyms A549 EGFR-/-
Accession CVCL_C3DB
Resource Identification Initiative To cite this cell line use: A549 EGFR Knockout (RRID:CVCL_C3DB)
Comments Population: Caucasian.
Knockout cell: Method=ZFN; HGNC; 3236; EGFR.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Children:
CVCL_C3DD (A549 EGFR High)CVCL_C3DC (A549 EGFR Low)CVCL_C3EU (A549 EGFRvIII High)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Sigma-Aldrich

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135816
D5S81811
D7S8208,11
D8S117913,14
D13S31711
D16S53911,12
D18S5114,17
D21S1129
FGA23
Penta D9
Penta E7,11
TH018,9.3
TPOX8,11
vWA14

Run an STR similarity search on this cell line
Web pages https://www.sigmaaldrich.com/catalog/product/sigma/atg002
Cross-references
Cell line databases/resources cancercelllines; CVCL_C3DB
Encyclopedic resources Wikidata; Q114310511
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5