Cellosaurus logo
expasy logo

Cellosaurus A549 EGFRvIII High (CVCL_C3EU)

[Text version]
Cell line name A549 EGFRvIII High
Accession CVCL_C3EU
Resource Identification Initiative To cite this cell line use: A549 EGFRvIII High (RRID:CVCL_C3EU)
Comments Population: Caucasian.
Characteristics: Expresses EGFR isoform vIII (EGFRvIII) at high level.
Knockout cell: Method=ZFN; HGNC; 3236; EGFR.
Transfected with: HGNC; 3236; EGFR (with p.Val30_Arg297del = EGFRvIII).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C3DB (A549 EGFR Knockout)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Web pages https://www.sigmaaldrich.com/catalog/product/sigma/atg005
Cross-references
Cell line databases/resources cancercelllines; CVCL_C3EU
Encyclopedic resources Wikidata; Q114310514
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5