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Cellosaurus A549 EGFR High (CVCL_C3DD)

[Text version]
Cell line name A549 EGFR High
Accession CVCL_C3DD
Resource Identification Initiative To cite this cell line use: A549 EGFR High (RRID:CVCL_C3DD)
Comments Population: Caucasian.
Characteristics: Expresses EGFR at high level (Sigma-Aldrich=ATG002).
Knockout cell: Method=ZFN; HGNC; HGNC:3236; EGFR.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3236; EGFR.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C3DB (A549 EGFR Knockout)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Sigma-Aldrich; ATG002
Cell line databases/resources cancercelllines; CVCL_C3DD
Encyclopedic resources Wikidata; Q114310510
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7