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Cellosaurus HeLa S3 penta KO (CVCL_C2VN)

[Text version]
Cell line name HeLa S3 penta KO
Accession CVCL_C2VN
Resource Identification Initiative To cite this cell line use: HeLa S3 penta KO (RRID:CVCL_C2VN)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:29912; CALCOCO2.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:6746; NBR1.
Knockout cell: Method=TALEN; HGNC; HGNC:17142; OPTN.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11280; SQSTM1.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11575; TAX1BP1.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0058 (HeLa S3)
Children:
CVCL_C2VP (HeLa S3 penta KO-ATG13 KO)CVCL_C2VQ (HeLa S3 penta KO-ATG14 KO)CVCL_C8QB (HeLa S3 penta KO-AZI2/TBKBP1 DKO clone 20)
CVCL_D2Q1 (HeLa S3 penta KO-AZI2/TBKBP1 DKO clone 26)CVCL_C2VR (HeLa S3 penta KO-TBK1 KO)CVCL_C2VS (HeLa S3 penta KO-ULK1/ULK2 DKO)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

DOI=10.1101/2023.09.25.559255
Adriaenssens E., Nguyen T.N., Sawa-Makarska J., Khuu G., Schuschnig M., Watts E.M., Shoebridge S., Csalyi K.D., Padman B.S., Lazarou M., Martens S.
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD.
bioRxiv 2023:09.25.559255-09.25.559255(2023)

Cross-references
Encyclopedic resources Wikidata; Q114311582
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7