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Cellosaurus HeLa S3 penta KO-AZI2/TBKBP1 DKO clone 20 (CVCL_C8QB)

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Cell line name HeLa S3 penta KO-AZI2/TBKBP1 DKO clone 20
Synonyms HeLa S3 NAP1/SINTBAD DKO/penta KO clone 20
Accession CVCL_C8QB
Resource Identification Initiative To cite this cell line use: HeLa S3 penta KO-AZI2/TBKBP1 DKO clone 20 (RRID:CVCL_C8QB)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; 29912; CALCOCO2.
Knockout cell: Method=CRISPR/Cas9; HGNC; 24002; AZI2.
Knockout cell: Method=CRISPR/Cas9; HGNC; 6746; NBR1.
Knockout cell: Method=TALEN; HGNC; 17142; OPTN.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11280; SQSTM1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11575; TAX1BP1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 30140; TBKBP1.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C2VN (HeLa S3 penta KO)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

DOI=10.1101/2023.09.25.559255
Adriaenssens E., Nguyen T.N., Sawa-Makarska J., Khuu G., Schuschnig M., Watts E.M., Shoebridge S., Csalyi K.D., Padman B.S., Lazarou M., Martens S.
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD.
bioRxiv 2023:09.25.559255-09.25.559255(2023)

Cross-references
Encyclopedic resources Wikidata; Q123031626
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2