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Cellosaurus ALL-VG (CVCL_C1ME)

[Text version]
Cell line name ALL-VG
Accession CVCL_C1ME
Resource Identification Initiative To cite this cell line use: ALL-VG (RRID:CVCL_C1ME)
Comments Karyotypic information: 45,XY,der(1)t(1;9),der(9)t(9;13),-13,der(16)t(16;22) (PubMed=18656692).
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: Proteome analysis by 2D-DE/MS.
Omics: SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Adult B acute lymphoblastic leukemia (NCIt: C9143)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C1MF (ALL-VG TKI-resistant)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
Publications

PubMed=18656692; DOI=10.1016/j.cancergencyto.2008.05.001
Baeumler J., Szuhai K., Falkenburg J.H.F., van Schie M.L.J., Ottmann O.G., Nijmeijer B.A.
Establishment and cytogenetic characterization of a human acute lymphoblastic leukemia cell line (ALL-VG) with ETV6/ABL1 rearrangement.
Cancer Genet. Cytogenet. 185:37-42(2008)

PubMed=28650474; DOI=10.1038/onc.2017.210; PMCID=PMC5666322
Zimmermannova O., Doktorova E., Stuchly J., Kanderova V., Kuzilkova D., Strnad H., Starkova J., Alberich-Jorda M., Falkenburg J.H.F., Trka J., Petrak J., Zuna J., Zaliova M.
An activating mutation of GNB1 is associated with resistance to tyrosine kinase inhibitors in ETV6-ABL1-positive leukemia.
Oncogene 36:5985-5994(2017)

Cross-references
Encyclopedic resources Wikidata; Q114310621
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number5