Cellosaurus cell line HEK293-CNG (CVCL

Cellosaurus HEK293-CNG (CVCL_C0RU)

[Text version]

Cell line name

HEK293-CNG

Synonyms

HEK-293-CNG; HEK293/CNG; CNG-HEK293; HEK CNG; HEK oCNG-NC-5

Accession

CVCL_C0RU

Resource Identification Initiative

To cite this cell line use: HEK293-CNG (RRID:CVCL_C0RU)

Comments

Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions).
Characteristics: Parent cell line for many ACTOne cell lines.
Genetic integration: Method=Transfection/transduction; Gene=RGD; 2367; Cnga2 (Note=With p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Miscellaneous: Has Codex Biosolutions catalog number CB-81200-200/AG-10200-200, but not distributed separately from children cell lines.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0045 (HEK293)
Children:

CVCL_C0RZ (ACTOne ADCYAP1R1)	CVCL_C0S0 (ACTOne ADORA1)	CVCL_C0S1 (ACTOne ADORA2A)
CVCL_C0S2 (ACTOne ADORA2B)	CVCL_C0S3 (ACTOne ADORA3)	CVCL_C0S4 (ACTOne ADRB1)
CVCL_C0S5 (ACTOne ADRB2)	CVCL_C0S6 (ACTOne AGTRL1)	CVCL_C0S8 (ACTOne AVPR2)
CVCL_C0S9 (ACTOne CALCR)	CVCL_C0SA (ACTOne CALCRL)	CVCL_C0SB (ACTOne CB1)
CVCL_C0SD (ACTOne CB2)	CVCL_C0SE (ACTOne CCR5)	CVCL_C0SF (ACTOne CRHR1)
CVCL_C0SG (ACTOne CRHR2)	CVCL_C0SH (ACTOne CXCR4)	CVCL_C0SI (ACTOne DRD1)
CVCL_C0SJ (ACTOne DRD2)	CVCL_C0SK (ACTOne DRD5)	CVCL_C0SL (ACTOne EDG1)
CVCL_C0SM (ACTOne FSHR)	CVCL_C0SN (ACTOne GCGR)	CVCL_C0SP (ACTOne GIPR)
CVCL_C0SQ (ACTOne GLP1R)	CVCL_C0SR (ACTOne GLP2R)	CVCL_C0SS (ACTOne GPR119)
CVCL_C0SX (ACTOne HTR1A)	CVCL_C0SY (ACTOne HTR1F)	CVCL_C0SZ (ACTOne HTR4)
CVCL_C0T0 (ACTOne HTR6)	CVCL_C0T1 (ACTOne HTR7B)	CVCL_C0T2 (ACTOne LHCGR)
CVCL_C0T3 (ACTOne MC1R)	CVCL_C0T4 (ACTOne MC3R)	CVCL_C0T5 (ACTOne MC4R)
CVCL_C0T6 (ACTOne MC5R)	CVCL_C0T7 (ACTOne MCHR1)	CVCL_C0T8 (ACTOne NPY1R)
CVCL_C0T9 (ACTOne NPY2R)	CVCL_C0TA (ACTOne NPY5R)	CVCL_C0TB (ACTOne OPRK1)
CVCL_C0TC (ACTOne OPRD1)	CVCL_C0TD (ACTOne OPRL1)	CVCL_C0TE (ACTOne OPRM1)
CVCL_C0TJ (ACTOne PPYR1)	CVCL_C0TK (ACTOne PTGDR2)	CVCL_C0TL (ACTOne PTGER2)
CVCL_C0TM (ACTOne PTGER4)	CVCL_C0TN (ACTOne PTGIR)	CVCL_C0TP (ACTOne PTHR1)
CVCL_C0TQ (ACTOne PTHR2)	CVCL_C0TR (ACTOne SCTR)	CVCL_C0TS (ACTOne SSTR5)
CVCL_C0TT (ACTOne TGR5)	CVCL_C0TU (ACTOne TSHR)	CVCL_C0TV (ACTOne VIPR1)
CVCL_C0TW (ACTOne VIPR2)	CVCL_C0RX (HEK293-CNG-Slc1a3)

Sex of cell

Female

Age at sampling

Fetus