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Cellosaurus ACTOne CALCR (CVCL_C0S9)

[Text version]
Cell line name ACTOne CALCR
Accession CVCL_C0S9
Resource Identification Initiative To cite this cell line use: ACTOne CALCR (RRID:CVCL_C0S9)
Comments Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions).
Genetic integration: Method=Transfection/transduction; Gene=RGD; 2367; Cnga2 (Note=With p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1440; CALCR.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0RU (HEK293-CNG)
Children:
CVCL_C0S7 (ACTOne AMY3)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages http://www.codexbiosolutions.com/wp-content/uploads/cb-80200-258.pdf
Cross-references
Encyclopedic resources Wikidata; Q112929136
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6