Cellosaurus ACTOne PTHR2 (CVCL_C0TQ)
| Cell line name | ACTOne PTHR2 |
|---|---|
| Synonyms | ACTOne PTH2R; HEK293-CNG-PTH2R |
| Accession | CVCL_C0TQ |
| Resource Identification Initiative | To cite this cell line use: ACTOne PTHR2 (RRID:CVCL_C0TQ) |
| Comments | Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions). Genetic integration: Method=Transfection/transduction; Gene=RGD; 2367; Cnga2 (Note=With p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9609; PTH2R. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C0RU (HEK293-CNG) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | http://www.codexbiosolutions.com/wp-content/uploads/cb-80200-228.pdf |
| Publications | PubMed=18087071; DOI=10.1177/1087057107309035 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112929192 |
| Entry history | |
| Entry creation | 23-Jun-2022 |
| Last entry update | 19-Dec-2024 |
| Version number | 6 |