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Cellosaurus UPCI-SCC-152 (CVCL_C058)

[Text version]
Cell line name UPCI-SCC-152
Synonyms UPCI:SCC152; UPCISCC152; SCC152
Accession CVCL_C058
Resource Identification Initiative To cite this cell line use: UPCI-SCC-152 (RRID:CVCL_C058)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Doubling time: 2 days (PubMed=29156801).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1899 ! UPCI-SCC-090
Sex of cell Male
Age at sampling 47Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3240; PubMed=29156801

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81811,12
D7S8209,10
D13S31711
D16S53912,13
TH017,9.3
TPOX8
vWA17

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Publications

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=24403267; DOI=10.1002/cam4.151; PMCID=PMC3892398
Kawakami H., Okamoto I., Terao K., Sakai K., Suzuki M., Ueda S., Tanaka K., Kuwata K., Morita Y., Ono K., Nishio K., Nishimura Y., Doi K., Nakagawa K.
Human papillomavirus DNA and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma.
Cancer Med. 2:933-941(2013)

PubMed=26045983; PMCID=PMC4449432
Ziemann F., Arenz A., Preising S., Wittekindt C., Klussmann J.P., Engenhart-Cabillic R., Wittig A.
Increased sensitivity of HPV-positive head and neck cancer cell lines to X-irradiation +/- cisplatin due to decreased expression of E6 and E7 oncoproteins and enhanced apoptosis.
Am. J. Cancer Res. 5:1017-1031(2015)

PubMed=28236344; DOI=10.1002/hed.24729; PMCID=PMC5392184
Walline H.M., Goudsmit C.M., McHugh J.B., Tang A.L., Owen J.H., Teh B.T., McKean E.L., Glover T.W., Graham M.P., Prince M.E.P., Chepeha D.B., Chinn S.B., Ferris R.L., Gollin S.M., Hoffmann T.K., Bier H., Brakenhoff R.H., Bradford C.R., Carey T.E.
University of Michigan Head and Neck Specialized Program of Research Excellence (SPORE) Program
Integration of high-risk human papillomavirus into cellular cancer-related genes in head and neck cancer cell lines.
Head Neck 39:840-852(2017)

PubMed=29156801; DOI=10.18632/oncotarget.21174; PMCID=PMC5689691
Kalu N.N., Mazumdar T., Peng S.-H., Shen L., Sambandam V., Rao X.-Y., Xi Y.-X., Li L.-R., Qi Y., Gleber-Netto F.O., Patel A., Wang J., Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.
Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.
Oncotarget 8:86369-86383(2017)

Cross-references
Cell line collections (Providers) ATCC; CRL-3240
Cell line databases/resources Cell_Model_Passport; SIDM00398
DepMap; ACH-001228
Encyclopedic resources Wikidata; Q54991684
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number19