ID   HaCaT-hGSTP1 ARE-SV40p-Luc2
AC   CVCL_B6YN
DR   CCRID; 4201PAT-CCTCC01845
DR   Wikidata; Q111733262
RX   Patent=CN113265423B;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2021113.
CC   Population: Caucasian.
CC   Characteristics: Expression of the luciferase reporter gene is under the control of the antioxidant response element (ARE) of GSTP1 (Patent=CN113265423B).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Tyr (c.535C>T); ClinVar=VCV000127815; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg282Trp (c.843_844CC>TT); Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P08659; Firefly luciferase (with optimized codon usage for mammalian expression).
CC   Derived from site: In situ; Back, skin, epidermis; UBERON=UBERON_0001068+UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0038 ! HaCaT
SX   Male
AG   62Y
CA   Spontaneously immortalized cell line
DT   Created: 17-03-22; Last updated: 29-06-23; Version: 5
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RX   Patent=CN113265423B;
RA   Chen T., Yin Q.-F.;
RT   "Construction and application of cell line containing luciferase
RT   reporter gene of human GSTP1 ARE.";
RL   Patent number CN113265423B, 23-Aug-2022.
//