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Cellosaurus BM2.2.3 (CVCL_B6V4)

[Text version]
Cell line name BM2.2.3
Accession CVCL_B6V4
Resource Identification Initiative To cite this cell line use: BM2.2.3 (RRID:CVCL_B6V4)
Comments Population: African; Kenyan.
Characteristics: Obtained from the grand-parent cell line that was subjected to 3 Gy of gamma-irradiation and selected for cells having mutations of MHC class 1 and class 2 genes with mAb against MHC proteins.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B6UP (BM2.2)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=8449221; DOI=10.1002/eji.1830230325
Uchanska-Ziegler B., Noessner E., Schenk A., Ziegler A., Schendel D.J.
Soluble T cell receptor-like properties of an HLA-B35-specific monoclonal antibody (TU165).
Eur. J. Immunol. 23:734-738(1993)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6V4
Encyclopedic resources Wikidata; Q111732975
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7