ID   BM2.2.3
AC   CVCL_B6V4
DR   cancercelllines; CVCL_B6V4
DR   Wikidata; Q111732975
RX   PubMed=8449221;
CC   Population: African; Kenyan.
CC   Characteristics: Obtained from the grand-parent cell line that was subjected to 3 Gy of gamma-irradiation and selected for cells having mutations of MHC class 1 and class 2 genes with mAb against MHC proteins.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Groin; UBERON=UBERON_0008337.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C2912; Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B6UP ! BM2.2
SX   Female
AG   5Y
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 02-05-24; Version: 6
//
RX   PubMed=8449221; DOI=10.1002/eji.1830230325;
RA   Uchanska-Ziegler B., Noessner E., Schenk A., Ziegler A., Schendel D.J.;
RT   "Soluble T cell receptor-like properties of an HLA-B35-specific
RT   monoclonal antibody (TU165).";
RL   Eur. J. Immunol. 23:734-738(1993).
//