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Cellosaurus BM2.2 (CVCL_B6UP)

[Text version]
Cell line name BM2.2
Synonyms BM 2.2
Accession CVCL_B6UP
Resource Identification Initiative To cite this cell line use: BM2.2 (RRID:CVCL_B6UP)
Comments Population: African; Kenyan.
Characteristics: Obtained from the parent cell line that was subjected to 3 Gy of gamma-irradiation and selected for cells having mutations of MHC class 1 and class 2 genes with mAb against MHC proteins (PubMed=3872842).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B6UM (BJAB-B95.8.6)
Children:
CVCL_B6V4 (BM2.2.3)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=3872842; DOI=10.1007/BF00375380
Spring B., Fonatsch C., Muller C., Pawelec G., Kompf J., Wernet P., Ziegler A.
Refinement of HLA gene mapping with induced B-cell line mutants.
Immunogenetics 21:277-291(1985)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6UP
Encyclopedic resources Wikidata; Q111732974
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7