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Cellosaurus EL4B7-2 (CVCL_B6PL)

[Text version]
Cell line name EL4B7-2
Accession CVCL_B6PL
Resource Identification Initiative To cite this cell line use: EL4B7-2 (RRID:CVCL_B6PL)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:101773; Cd86.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Caution: There are two EL4 Cd86 (B7-2) transfected cell lines: EL4B7-2 (Cellosaurus=CVCL_B6PL) and EL4-B7-2 (Cellosaurus=CVCL_B6PH).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse precursor T cell lymphoblastic lymphoma/leukemia (NCIt: C21925)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6N.
Hierarchy Parent: CVCL_0255 (EL4)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10477562; DOI=10.4049/jimmunol.163.6.2999
Krummel M.F., Heath W.R., Allison J.
Differential coupling of second signals for cytotoxicity and proliferation in CD8+ T cell effectors: amplification of the lytic potential by B7.
J. Immunol. 163:2999-3006(1999)

Cross-references
Encyclopedic resources Wikidata; Q111733185
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7