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Cellosaurus EL4-B7-2 (CVCL_B6PH)

[Text version]
Cell line name EL4-B7-2
Synonyms B7-2-EL4
Accession CVCL_B6PH
Resource Identification Initiative To cite this cell line use: EL4-B7-2 (RRID:CVCL_B6PH)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:101773; Cd86.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Caution: There are two EL4 Cd86 (B7-2) transfected cell lines: EL4B7-2 (Cellosaurus=CVCL_B6PL) and EL4-B7-2 (Cellosaurus=CVCL_B6PH).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse precursor T cell lymphoblastic lymphoma/leukemia (NCIt: C21925)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6N.
Hierarchy Parent: CVCL_0255 (EL4)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10075975; DOI=10.1084/jem.189.6.919; PMCID=PMC2193048
Stremmel C., Greenfield E.A., Howard E., Freeman G.J., Kuchroo V.K.
B7-2 expressed on EL4 lymphoma suppresses antitumor immunity by an interleukin 4-dependent mechanism.
J. Exp. Med. 189:919-930(1999)

Cross-references
Encyclopedic resources Wikidata; Q111733182
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number7