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Cellosaurus BALB/3T3 clone A31 ts2 (CVCL_B5VE)

[Text version]
Cell line name BALB/3T3 clone A31 ts2
Synonyms ts-2; ts2
Accession CVCL_B5VE
Resource Identification Initiative To cite this cell line use: BALB/3T3 clone A31 ts2 (RRID:CVCL_B5VE)
Comments Characteristics: Temperature sensitive. At the non-permissive temperature of 38 Celsius cease to proliferate due to a defect in DNA synthesis (PubMed=182373).
Doubling time: 35-40 hours (Note=At 33 Celsius) (PubMed=182373).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0184 (BALB/3T3 clone A31)
Children:
CVCL_B5VJ (BALB/3T3 clone A31 ts2-TG-31)CVCL_B5VF (BALB/3T3 clone A31 ts2R)
Sex of cell Sex unspecified
Age at sampling 14-17FD
Category Transformed cell line
Publications

PubMed=182373; DOI=10.1016/0092-8674(76)90028-3
Slater M.L., Ozer H.L.
Temperature-sensitive mutants of Balb/3T3 cells: description of a mutant affected in cellular and polyoma virus DNA synthesis.
Cell 7:289-295(1976)

CLPUB00677
Jha K.K., Ozer H.L.
Genetic studies with a mutant mouse cell, ts-2 Balb/3T3, with a temperature sensitive defect in DNA synthesis.
Genetics 86 Suppl. 2:S32-S33(1977)

PubMed=6933701; DOI=10.1007/BF01538640
Jha K.K., Siniscalco M., Ozer H.L.
Temperature-sensitive mutants of Balb/3T3 cells. III. Hybrids between ts2 and other mouse mutant cells affected in DNA synthesis and correction of ts2 defect by human X chromosome.
Somatic Cell Genet. 6:603-614(1980)

Cross-references
Encyclopedic resources Wikidata; Q111732949
Entry history
Entry creation17-Mar-2022
Last entry update19-Dec-2024
Version number5