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Cellosaurus V79-hCYP1A2-hSULT1A1 (CVCL_A2GY)

[Text version]
Cell line name V79-hCYP1A2-hSULT1A1
Synonyms V79-CYP1A2-SULT1A1
Accession CVCL_A2GY
Resource Identification Initiative To cite this cell line use: V79-hCYP1A2-hSULT1A1 (RRID:CVCL_A2GY)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2596; CYP1A2.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11453; SULT1A1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4V39 (V79-hCYP1A2)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=14729582; DOI=10.1093/carcin/bgh077
Glatt H.-R., Pabel U., Meinl W., Frederiksen H., Frandsen H., Muckel E.
Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes.
Carcinogenesis 25:801-807(2004)

PubMed=31112310; DOI=10.1002/em.22309
Zhu N., Hu K.-Q., Li Z.-H., Chen Y.-T., Liu Y.-G.
Micronuclei formation by promutagens in metabolism-incompetent V79 cells interacting with activation-proficient cells in various experimental settings.
Environ. Mol. Mutagen. 61:224-234(2020)

PubMed=33035519; DOI=10.1016/j.cbi.2020.109283
Yu H., Li Z.-H., Yang Z.-Y., Song M.-Q., Liu Y.-G.
1-Methylpyrene induces chromosome loss and mitotic apparatus damage in a Chinese hamster V79-derived cell line expressing both human CYP1A2 and sulfotransferase 1A1.
Chem. Biol. Interact. 332:109283.1-109283.8(2020)

Cross-references
Encyclopedic resources Wikidata; Q105511673
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number7