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Cellosaurus GP11 (CVCL_A2FK)

[Text version]
Cell line name GP11
Accession CVCL_A2FK
Resource Identification Initiative To cite this cell line use: GP11 (RRID:CVCL_A2FK)
Comments Characteristics: Expresses GNRH1, GPR54 and ESR2, but not ESR1. Secretes GnRH peptides and responds to kisspeptin (PubMed=32432378).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Fetal brain, hypothalamus, preoptic area; UBERON=UBERON_0006238+UBERON_0001928.
Cell type: GnRH neuron; CL=CL_0011111.
Species of origin Capra hircus (Goat) (NCBI Taxonomy: 9925)
Breed/subspecies: Shiba; VBO=VBO_0017514.
Originate from same individual CVCL_A2FJ ! GA28
CVCL_A2FL ! GP31
CVCL_A2FM ! GP64
Sex of cell Female
Age at sampling 118FD
Category Transformed cell line
Publications

PubMed=32432378; DOI=10.1111/jne.12857
Suetomi Y., Tatebayashi R., Sonoda S., Munetomo A., Matsuyama S., Inoue N., Uenoyama Y., Takeuchi Y., Tsukamura H., Ohkura S., Matsuda F.
Establishment of immortalised cell lines derived from female Shiba goat KNDy and GnRH neurones.
J. Neuroendocrinol. 32:e12857.1-e12857.18(2020)

Cross-references
Cell line collections (Providers) ABM; T0865
Encyclopedic resources Wikidata; Q105507463
Entry history
Entry creation12-Jan-2021
Last entry update19-Dec-2024
Version number9