Cellosaurus GP64 (CVCL_A2FM)
| Cell line name | GP64 |
|---|---|
| Accession | CVCL_A2FM |
| Resource Identification Initiative | To cite this cell line use: GP64 (RRID:CVCL_A2FM) |
| Comments | Characteristics: Expresses kisspeptin and ER-alpha both at the mRNA and protein levels and responds to estrogen, similar to endogenous preoptic area kisspeptin neurons, which mediate estrogen positive feedback and regulate GnRH/LH surge (PubMed=33100283). Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Fetal brain, hypothalamus, preoptic area; UBERON=UBERON_0006238+UBERON_0001928. Cell type: Kisspeptin neuron; CL=CL_4023130. |
| Species of origin | Capra hircus (Goat)
(NCBI Taxonomy: 9925)
Breed/subspecies: Shiba; VBO=VBO_0017514. |
| Originate from same individual | CVCL_A2FJ ! GA28 CVCL_A2FK ! GP11 CVCL_A2FL ! GP31 |
| Sex of cell | Female |
| Age at sampling | 118FD |
| Category | Transformed cell line |
| Publications | PubMed=33100283; DOI=10.1262/jrd.2020-053; PMCID=PMC7902218 |
| Cross-references | |
| Cell line collections (Providers) | ABM; T0867 |
| Encyclopedic resources | Wikidata; Q105507470 |
| Entry history | |
| Entry creation | 12-Jan-2021 |
| Last entry update | 19-Dec-2024 |
| Version number | 9 |