ID   GP11
AC   CVCL_A2FK
DR   ABM; T0865
DR   Wikidata; Q105507463
RX   PubMed=32432378;
CC   Characteristics: Expresses GNRH1, GPR54 and ESR2, but not ESR1. Secretes GnRH peptides and responds to kisspeptin (PubMed=32432378).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Fetal brain, hypothalamus, preoptic area; UBERON=UBERON_0006238+UBERON_0001928.
CC   Cell type: GnRH neuron; CL=CL_0011111.
CC   Breed/subspecies: Shiba; VBO=VBO_0017514.
OX   NCBI_TaxID=9925; ! Capra hircus (Goat)
OI   CVCL_A2FJ ! GA28
OI   CVCL_A2FL ! GP31
OI   CVCL_A2FM ! GP64
SX   Female
AG   118FD
CA   Transformed cell line
DT   Created: 12-01-21; Last updated: 19-12-24; Version: 9
//
RX   PubMed=32432378; DOI=10.1111/jne.12857;
RA   Suetomi Y., Tatebayashi R., Sonoda S., Munetomo A., Matsuyama S.,
RA   Inoue N., Uenoyama Y., Takeuchi Y., Tsukamura H., Ohkura S.,
RA   Matsuda F.;
RT   "Establishment of immortalised cell lines derived from female Shiba
RT   goat KNDy and GnRH neurones.";
RL   J. Neuroendocrinol. 32:e12857.1-e12857.18(2020).
//