ID   MGPK alphaVbeta6-C5
SY   MGPKalphaVbeta6-C5; MGPK aVb6-C5; MGPKaVb6-C5
DR   Wikidata; Q108820904
RX   PubMed=34092457;
CC   Problematic cell line: Misidentified. Grand-parent cell line (LF-BK) was originally thought to be of bovine origin but originates from pig (PubMed=25617444).
CC   Virology: Combined treatment of the parent cell line with BVDV NS5A siRNA, interferon alpha and ribavirin has cured the cell line from bovine viral diarrhea virus (BVDV) infection (PubMed=34092457).
CC   Virology: Susceptible to infection by foot-and-mouth disease virus (PubMed=34092457).
CC   Transfected with: VGNC; 30323; Bovine ITGAV.
CC   Transfected with: VGNC; 30331; Bovine ITGB6.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
OX   NCBI_TaxID=9823; ! Sus scrofa (Pig)
HI   CVCL_RX27 ! LFBK-alphaVbeta6
SX   Sex unspecified
AG   Age unspecified
CA   Spontaneously immortalized cell line
DT   Created: 23-09-21; Last updated: 21-03-23; Version: 4
RX   PubMed=34092457; DOI=10.1016/j.biologicals.2021.05.003;
RA   LaRocco M.A., Ahmed Z., Rodriguez-Calzada M., Azzinaro P.A.,
RA   Barrette R., Krug P., Rodriguez L.L., de Los Santos T., Medina G.N.;
RT   "An adventitious agent-free clonal cell line that is highly
RT   susceptible to foot -and-mouth disease virus.";
RL   Biologicals 72:33-41(2021).