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Cellosaurus SCMC-L1 (CVCL_7125)

[Text version]
Cell line name SCMC-L1
Synonyms SCMC-L-1; SCMCL-L1; Saitama Children's Medical Center-Leukemia 1
Accession CVCL_7125
Secondary accession CVCL_G317
Resource Identification Initiative To cite this cell line use: SCMC-L1 (RRID:CVCL_7125)
Comments Population: Japanese.
Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
Sequence variations
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged (NCIt: C80342)
B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) (ORDO: Orphanet_585918)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 4M
Category Cancer cell line
Publications

CLPUB00110
Hayashi Y., Hanada R., Moriwaki K., Yamamoto K., Imaizumi S., Hirata A., Nishida T.
Establishment and characterization of cell lines derived from malignant tumors in children.
Saitama Shoni Iryo Senta Igaku-shi 8:16-23(1991)

CLPUB00111
Hayashi Y., Kawamura M., Kobayashi S., Moriwaki K., Kobayashi M., Bessho F., Hanada R., Yamamoto K., Mori T., Nakazawa S., Yaginuma Y., Honma Y., Hozumi M.
Establishment and characterization of cell lines derived from childhood leukemias.
Int. J. Hematol. 57 Suppl. 1:124-124(1993)

PubMed=7647001; DOI=10.1111/j.1365-2141.1995.tb05591.x
Ito E., Kasai M., Hayashi Y., Toki T., Arai K., Yokoyama S., Kato K., Tachibana N., Yamamoto M., Yokoyama M.
Expression of erythroid-specific genes in acute megakaryoblastic leukaemia and transient myeloproliferative disorder in Down's syndrome.
Br. J. Haematol. 90:607-614(1995)

PubMed=10233379; DOI=10.1111/j.1365-2141.1999.01284.x
Xu F., Taki T., Yang H.W., Hanada R., Hongo T., Ohnishi H., Kobayashi M., Bessho F., Yanagisawa M., Hayashi Y.
Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children.
Br. J. Haematol. 105:155-162(1999)

PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines.
Leuk. Res. 24:255-262(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1
Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.
Corrigendum to: Frequent microsatellite instability and BAX mutations in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24 (2000), 255-262.
Leuk. Res. 25:275-278(2001)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Drexler H.G., Quentmeier H., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)

PubMed=29786757; DOI=10.1007/s12185-018-2474-7
Tomoyasu C., Imamura T., Tomii T., Yano M., Asai D., Goto H., Shimada A., Sanada M., Iwamoto S., Takita J., Minegishi M., Inukai T., Sugita K., Hosoi H.
Copy number abnormality of acute lymphoblastic leukemia cell lines based on their genetic subtypes.
Int. J. Hematol. 108:312-318(2018)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

Cross-references
Encyclopedic resources Wikidata; Q54952452
Polymorphism and mutation databases Cosmic; 998688
Cosmic; 1037738
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number22