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Cellosaurus HMT-3522 (CVCL_6855)

[Text version]
Cell line name HMT-3522
Synonyms HMT3522
Accession CVCL_6855
Resource Identification Initiative To cite this cell line use: HMT-3522 (RRID:CVCL_6855)
Comments Population: Caucasian.
Characteristics: EGF dependent.
Donor information: Established from a nontumorigenic fibrocystic breast lesion (PubMed=3558253).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_2499 (HMT-3522 S1)CVCL_2500 (HMT-3522 S2)
Sex of cell Female
Age at sampling 50Y
Category Spontaneously immortalized cell line

PubMed=3558253; DOI=10.1007/BF02623578
Briand P., Petersen O.W., van Deurs B.
A new diploid nontumorigenic human breast epithelial cell line isolated and propagated in chemically defined medium.
In Vitro Cell. Dev. Biol. 23:181-188(1987)

Leibovitz A.
Cell lines from human breast.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.161-184; Academic Press; New York (1994)

PubMed=7828152; DOI=10.1016/0165-4608(94)90089-2
Nielsen K.V., Madsen M.W., Briand P.
In vitro karyotype evolution and cytogenetic instability in the non-tumorigenic human breast epithelial cell line HMT-3522.
Cancer Genet. Cytogenet. 78:189-199(1994)

PubMed=7982476; DOI=10.1006/excr.1994.1355
Moyret C., Madsen M.W., Cooke J., Briand P., Theillet C.
Gradual selection of a cellular clone presenting a mutation at codon 179 of the p53 gene during establishment of the immortalized human breast epithelial cell line HMT-3522.
Exp. Cell Res. 215:380-385(1994)

PubMed=7495986; DOI=10.1006/scbi.1995.0021
Weaver V.M., Howlett A.R., Langton-Webster B.C., Petersen O.W., Bissell M.J.
The development of a functionally relevant cell culture model of progressive human breast cancer.
Semin. Cancer Biol. 6:175-184(1995)

Anatomy/cell type resources BTO; BTO:0003884
Encyclopedic resources Wikidata; Q54889967
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number14