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Cellosaurus HMT-3522 S1 (CVCL_2499)

[Text version]
Cell line name HMT-3522 S1
Synonyms HMT-3522-S1; HMT-3522S1; HMT3522S1; S1; S-1; HMT-3522/wt
Accession CVCL_2499
Resource Identification Initiative To cite this cell line use: HMT-3522 S1 (RRID:CVCL_2499)
Comments Part of: GrayJW breast cancer cell line panel.
Population: Caucasian.
Doubling time: 40.14 hours (GrayJW panel).
Omics: Deep proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Donor information: Established from a nontumorigenic fibrocystic breast lesion (from parent cell line).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6855 (HMT-3522)
Sex of cell Female
Age at sampling 50Y
Category Spontaneously immortalized cell line
Web pages https://www.synapse.org/#!Synapse:syn2346643/wiki/62255

PubMed=7982476; DOI=10.1006/excr.1994.1355
Moyret C., Madsen M.W., Cooke J., Briand P., Theillet C.
Gradual selection of a cellular clone presenting a mutation at codon 179 of the p53 gene during establishment of the immortalized human breast epithelial cell line HMT-3522.
Exp. Cell Res. 215:380-385(1994)

Briand P., Nielsen K.V., Madsen M.W., Petersen O.W.
Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal.
Cancer Res. 56:2039-2044(1996)

PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004
Kenny P.A., Lee G.Y., Myers C.A., Neve R.M., Semeiks J.R., Spellman P.T., Lorenz K., Lee E.H., Barcellos-Hoff M.H., Petersen O.W., Gray J.W., Bissell M.J.
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.
Mol. Oncol. 1:84-96(2007)

PubMed=18316601; DOI=10.1158/0008-5472.CAN-07-2225
Rizki A., Weaver V.M., Lee S.-Y., Rozenberg G.I., Chin K., Myers C.A., Bascom J.L., Mott J.D., Semeiks J.R., Grate L.R., Mian I.S., Borowsky A.D., Jensen R.A., Idowu M.O., Chen F.-Q., Chen D.J., Petersen O.W., Gray J.W., Bissell M.J.
A human breast cell model of preinvasive to invasive transition.
Cancer Res. 68:1378-1387(2008)

PubMed=22414580; DOI=10.1158/0008-5472.CAN-11-3711
Geiger T., Madden S.F., Gallagher W.M., Cox J., Mann M.
Proteomic portrait of human breast cancer progression identifies novel prognostic markers.
Cancer Res. 72:2428-2439(2012)

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C.B., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y.-L., Mills G.B., Cho R.J., Collisson E.A., van 't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

Cell line collections (Providers) ECACC; 98102210
Cell line databases/resources LINCS_HMS; 51119
Anatomy/cell type resources BTO; BTO:0006484
Chemistry resources PharmacoDB; S1_1340_2019
Encyclopedic resources Wikidata; Q54889968
Experimental variables resources EFO; EFO_0001191
Gene expression databases ArrayExpress; E-TABM-244
GEO; GSM1219374
GEO; GSM1219375
GEO; GSM1219376
GEO; GSM1219377
GEO; GSM1219378
Polymorphism and mutation databases Cosmic; 889085
Proteomic databases PRIDE; PXD000309
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18