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Cellosaurus HMT-3522 S1 (CVCL_2499)

[Text version]
Cell line name HMT-3522 S1
Synonyms HMT-3522-S1; HMT3522 S1; HMT-3522S1; HMT3522S1; S1; S-1; HMT-3522/wt; HMEC S1
Accession CVCL_2499
Resource Identification Initiative To cite this cell line use: HMT-3522 S1 (RRID:CVCL_2499)
Comments Part of: JWGray breast cancer cell line panel.
Population: Caucasian.
Doubling time: 40.14 hours (JWGray panel).
Omics: Deep proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Donor information: Established from a nontumorigenic fibrocystic breast lesion (from parent cell line).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6855 (HMT-3522)
Sex of cell Female
Age at sampling 50Y
Category Spontaneously immortalized cell line
Web pages https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
Publications

PubMed=7982476; DOI=10.1006/excr.1994.1355
Moyret C., Madsen M.W., Cooke J., Briand P., Theillet C.
Gradual selection of a cellular clone presenting a mutation at codon 179 of the p53 gene during establishment of the immortalized human breast epithelial cell line HMT-3522.
Exp. Cell Res. 215:380-385(1994)

PubMed=8616848
Briand P., Nielsen K.V., Madsen M.W., Petersen O.W.
Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal.
Cancer Res. 56:2039-2044(1996)

PubMed=16849555; DOI=10.1158/0008-5472.CAN-06-0515; PMCID=PMC2933218
Fournier M.V., Martin K.J., Kenny P.A., Xhaja K., Bosch I., Yaswen P., Bissell M.J.
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer.
Cancer Res. 66:7095-7102(2006)

PubMed=18516279; DOI=10.1016/j.molonc.2007.02.004; PMCID=PMC2391005
Kenny P.A., Lee G.Y., Myers C.A., Neve R.M., Semeiks J.R., Spellman P.T., Lorenz K., Lee E.H., Barcellos-Hoff M.H., Petersen O.W., Gray J.W., Bissell M.J.
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.
Mol. Oncol. 1:84-96(2007)

PubMed=18316601; DOI=10.1158/0008-5472.CAN-07-2225; PMCID=PMC2662716
Rizki A., Weaver V.M., Lee S.-Y., Rozenberg G.I., Chin K., Myers C.A., Bascom J.L., Mott J.D., Semeiks J.R., Grate L.R., Mian I.S., Borowsky A.D., Jensen R.A., Idowu M.O., Chen F.-Q., Chen D.J., Petersen O.W., Gray J.W., Bissell M.J.
A human breast cell model of preinvasive to invasive transition.
Cancer Res. 68:1378-1387(2008)

PubMed=22414580; DOI=10.1158/0008-5472.CAN-11-3711
Geiger T., Madden S.F., Gallagher W.M., Cox J., Mann M.
Proteomic portrait of human breast cancer progression identifies novel prognostic markers.
Cancer Res. 72:2428-2439(2012)

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110; PMCID=PMC3937590
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C.B., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y.-L., Mills G.B., Cho R.J., Collisson E.A., van 't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

Cross-references
Cell line collections (Providers) ECACC; 98102210
Cell line databases/resources LINCS_HMS; 51119
Anatomy/cell type resources BTO; BTO_0006484
Chemistry resources PharmacoDB; S1_1340_2019
Encyclopedic resources Wikidata; Q54889968
Experimental variables resources EFO; EFO_0001189
EFO; EFO_0001191
Gene expression databases ArrayExpress; E-TABM-244
GEO; GSM200612
GEO; GSM200739
GEO; GSM200740
GEO; GSM200741
GEO; GSM200742
GEO; GSM200743
GEO; GSM1219374
GEO; GSM1219375
GEO; GSM1219376
GEO; GSM1219377
GEO; GSM1219378
Polymorphism and mutation databases Cosmic; 889085
Proteomic databases PRIDE; PXD000309
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21