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Cellosaurus 2V6.11 (CVCL_6355)

[Text version]
Cell line name 2V6.11
Accession CVCL_6355
Resource Identification Initiative To cite this cell line use: 2V6.11 (RRID:CVCL_6355)
Comments Characteristics: Adenovirus 5 E4 34kda protein is expressed under the control of an ecdysone-inducible promoter (PubMed=15141036).
Characteristics: Transfected with the pVgRXR vector that contains the VgEcR fusion protein under the control of a CMV promoter and RXRA under the control of a RSV promoter as well as BleoR (PubMed=15141036).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10477; RXRA.
Genetic integration: Method=Transfection; Gene=FlyBase_Gene; FBgn0000546; EcR (Note=With p.Met1_Val221del, as 2nd part of VgECR).
Genetic integration: Method=Transfection; Gene=UniProtKB; Q6VGT3; Adenovirus 5 E4 34kda protein.
Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Thr412del, as 1st part of VgECR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E3D4 (293VgRXR)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2784; CLS=305147

Markers:
AmelogeninX
CSF1PO7,11,12
D2S133819
D3S135815,17
D5S8188,9
D6S104311
D7S82011
D8S117912,14
D12S39119,21
D13S31712,14
D16S5399,13
D18S5117,19
D19S43315,18
D21S1128,30.2
FGA23
Penta D9,10
Penta E7,15
TH017,9.3
TPOX11
vWA16,19

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Web pages http://jhu.technologypublisher.com/technology/16640
Publications

PubMed=15141036; DOI=10.1093/nar/gkh593; PMCID=PMC419473
Mohammadi E.S., Ketner E.A., Johns D.C., Ketner G.
Expression of the adenovirus E4 34k oncoprotein inhibits repair of double strand breaks in the cellular genome of a 293-based inducible cell line.
Nucleic Acids Res. 32:2652-2659(2004)

Cross-references
Cell line collections (Providers) ATCC; CRL-2784 - Discontinued
ATCC; JHU-67 - Discontinued
CLS; 305147
Cell line databases/resources CLO; CLO_0001274
CCRID; 3101HUMGNHu26
Biological sample resources BioSample; SAMN03471789
Encyclopedic resources Wikidata; Q54584619
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number23