ID   2V6.11
AC   CVCL_6355
DR   CLO; CLO_0001274
DR   ATCC; CRL-2784
DR   ATCC; JHU-67
DR   BioSample; SAMN03471789
DR   CCRID; 3101HUMGNHu26
DR   CLS; 305147
DR   Wikidata; Q54584619
RX   PubMed=15141036;
WW   http://jhu.technologypublisher.com/technology/16640
CC   Characteristics: Adenovirus 5 E4 34kda protein is expressed under the control of an ecdysone-inducible promoter (PubMed=15141036).
CC   Characteristics: Transfected with the pVgRXR vector that contains the VgEcR fusion protein under the control of a CMV promoter and RXRA under the control of a RSV promoter as well as BleoR (PubMed=15141036).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10477; RXRA.
CC   Genetic integration: Method=Transfection; Gene=FlyBase_Gene; FBgn0000546; EcR (Note=With p.Met1_Val221del, as 2nd part of VgECR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; Q6VGT3; Adenovirus 5 E4 34kda protein.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Thr412del, as 1st part of VgECR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Discontinued: ATCC; CRL-2784; true.
CC   Discontinued: ATCC; JHU-67; true.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
ST   Source(s): ATCC=CRL-2784; CLS=305147
ST   Amelogenin: X
ST   CSF1PO: 7,11,12
ST   D12S391: 19,21
ST   D13S317: 12,14
ST   D16S539: 9,13
ST   D18S51: 17,19
ST   D19S433: 15,18
ST   D21S11: 28,30.2
ST   D2S1338: 19
ST   D3S1358: 15,17
ST   D5S818: 8,9
ST   D6S1043: 11
ST   D7S820: 11
ST   D8S1179: 12,14
ST   FGA: 23
ST   Penta D: 9,10
ST   Penta E: 7,15
ST   TH01: 7,9.3
ST   TPOX: 11
ST   vWA: 16,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E3D4 ! 293VgRXR
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 23
//
RX   PubMed=15141036; DOI=10.1093/nar/gkh593; PMCID=PMC419473;
RA   Mohammadi E.S., Ketner E.A., Johns D.C., Ketner G.;
RT   "Expression of the adenovirus E4 34k oncoprotein inhibits repair of
RT   double strand breaks in the cellular genome of a 293-based inducible
RT   cell line.";
RL   Nucleic Acids Res. 32:2652-2659(2004).
//