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Cellosaurus 293VgRXR (CVCL_E3D4)

[Text version]
Cell line name 293VgRXR
Accession CVCL_E3D4
Resource Identification Initiative To cite this cell line use: 293VgRXR (RRID:CVCL_E3D4)
Comments Characteristics: Transfected with the pVgRXR vector that contains the VgEcR fusion protein under the control of a CMV promoter and RXRA under the control of a RSV promoter as well as BleoR (PubMed=15141036).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10477; RXRA.
Genetic integration: Method=Transfection; Gene=FlyBase_Gene; FBgn0000546; EcR (Note=With p.Met1_Val221del, as 2nd part of VgECR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Thr412del, as 1st part of VgECR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Children:
CVCL_6355 (2V6.11)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=15141036; DOI=10.1093/nar/gkh593; PMCID=PMC419473
Mohammadi E.S., Ketner E.A., Johns D.C., Ketner G.
Expression of the adenovirus E4 34k oncoprotein inhibits repair of double strand breaks in the cellular genome of a 293-based inducible cell line.
Nucleic Acids Res. 32:2652-2659(2004)

Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2