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Cellosaurus MCF-10A-neoT (CVCL_5554)

[Text version]
Cell line name MCF-10A-neoT
Synonyms MCF-10A neoT; MCF-10AneoT; MCF10AneoT; MCF10-AneoT
Accession CVCL_5554
Resource Identification Initiative To cite this cell line use: MCF-10A-neoT (RRID:CVCL_5554)
Comments Transfected with: HGNC; 5173; HRAS (with p.Gly12Val).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
CVCL_5555 (MCF-10AT)CVCL_WM98 (MCF10AT1k.cl2)
Sex of cell Female
Age at sampling 36Y
Category Transformed cell line

PubMed=1885681; DOI=10.1242/jcs.99.2.453
Russo J., Tait L., Russo I.H.
Morphological expression of cell transformation induced by c-Ha-ras oncogene in human breast epithelial cells.
J. Cell Sci. 99:453-463(1991)

PubMed=2009132; DOI=10.1002/mc.2940040106
Basolo F., Elliott J., Tait L., Chen X.-Q., Maloney T.M., Russo I.H., Pauley R.J., Momiki S., Caamano J., Klein-Szanto A.J.P., Koszalka M., Russo J.
Transformation of human breast epithelial cells by c-Ha-ras oncogene.
Mol. Carcinog. 4:25-35(1991)

PubMed=11261825; DOI=10.1023/A:1006461422273
Santner S.J., Dawson P.J., Tait L., Soule H.D., Eliason J.F., Mohamed A.N., Wolman S.R., Heppner G.H., Miller F.R.
Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells.
Breast Cancer Res. Treat. 65:101-110(2001)

Anatomy/cell type resources BTO; BTO:0005127
Chemistry resources ChEMBL-Cells; CHEMBL4295460
ChEMBL-Targets; CHEMBL4296464
PubChem_Cell_line; CVCL_5554
Encyclopedic resources Wikidata; Q54904297
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number17