Cellosaurus MT-4 (CVCL_2632)
Cell line name | MT-4 | ||||||||||||||||||||||||||||||||
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Synonyms | MT4 | ||||||||||||||||||||||||||||||||
Accession | CVCL_2632 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: MT-4 (RRID:CVCL_2632) | ||||||||||||||||||||||||||||||||
Comments | Problematic cell line: Partially contaminated. Two different lots formerly distributed by NIH-ARP; 13 P7 3/9/92 and 150048; were shown not to be authentic MT-4 (PubMed=9261343; PubMed=31554688). Population: Japanese. Characteristics: Was established by co-cultivation of cells from a 50 year old male T-cell leukemia patient with cord leukocytes from a male infant (CelloPub=CLPUB00542). Virology: HTLV-1 producing cell line. Expresses Tax. Is permissive for replication of an HIV-1 gp41 mutant lacking the cytoplasmic tail. Doubling time: ~30 hours (Note=Lot 102799) (JCRB=JCRB1216). Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1). Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168. Cell type: T-cell; CL=CL_0000084. | ||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Sex of cell | Male | ||||||||||||||||||||||||||||||||
Age at sampling | <1D | ||||||||||||||||||||||||||||||||
Category | Transformed cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): JCRB=JCRB0135; JCRB=JCRB1216; PubMed=31554688; PubMed=32938764 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Web pages | https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/m/cell-lines-detail-117.html | ||||||||||||||||||||||||||||||||
Publications | CLPUB00542 PubMed=2413616; DOI=10.1016/0042-6822(85)90010-8 PubMed=1765142; DOI=10.1016/0014-5793(91)81402-t PubMed=1364232 PubMed=8927062 PubMed=8957066; DOI=10.1111/j.1349-7006.1996.tb03112.x; PMCID=PMC5920998 PubMed=9261343; DOI=10.1128/JVI.71.9.6277-6278.1997; PMCID=PMC191899 PubMed=29892436; DOI=10.1098/rsos.172472; PMCID=PMC5990783 PubMed=31554688; DOI=10.1128/JVI.01390-19; PMCID=PMC6880167 PubMed=32938764; DOI=10.1128/JVI.01334-20; PMCID=PMC7654282 | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Cell line collections (Providers) | BEI_Resources; ARP-120
ECACC; 08081402 JCRB; JCRB0135 - Discontinued JCRB; JCRB1216 - Discontinued JCRB; NIHS0145 - Discontinued JCRB; NIHS0529 - Discontinued KCB; KCB 200308YJ | ||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0007891
CLDB; cl3594 CLDB; cl3599 | ||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0003030 | ||||||||||||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03470803
BioSample; SAMN03472442 | ||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308375
ChEMBL-Targets; CHEMBL388 PubChem_Cell_line; CVCL_2632 | ||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54906940 | ||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 1191697 | ||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||
Last entry update | 10-Sep-2024 | ||||||||||||||||||||||||||||||||
Version number | 25 |