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Cellosaurus HCA7 colony 1 (CVCL_2469)

[Text version]
Cell line name HCA7 colony 1
Synonyms HCA-7 Colony 1; HCA-7 Colony1; HCA-7 Col-1; Colony-1; Col-1; Col 1
Accession CVCL_2469
Resource Identification Initiative To cite this cell line use: HCA7 colony 1 (RRID:CVCL_2469)
Comments Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Glu582fs*20 (c.1742_1743insA); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 16712; FBXW7; Simple; p.Arg479Ter (c.1435C>T); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro301Glnfs*44 (c.898delC); Zygosity=Unspecified (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0289 (HCA7)
Children:
CVCL_C1KR (HCA7 colony 1 C1Y1-15)CVCL_C1KM (HCA7 colony 1 C1Y1-6)CVCL_C1KS (HCA7 colony 1 C1Y1C-3)
CVCL_C1KT (HCA7 colony 1 C1Y1C-5)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=8410493; DOI=10.1002/path.1711700407
Marsh K.A., Stamp G.W.H., Kirkland S.C.
Isolation and characterization of multiple cell types from a single human colonic carcinoma: tumourigenicity of these cell types in a xenograft system.
J. Pathol. 170:441-450(1993)

PubMed=9050010; DOI=10.1007/PL00004930
Holliday N.D., Tough I.R., Cox H.M.
Inhibition of cyclic AMP-dependent chloride secretion by PP receptors and alpha 2-adrenoceptors in a human colonic epithelial cell line.
Naunyn Schmiedebergs Arch. Pharmacol. 355:183-189(1997)

CLPUB00715
Holliday N.D.
Functional expression of native and mutant Y1 receptors in stably transfected adenocarcinoma cell lines.
Thesis PhD (1998); University College London; London; United Kingdom

Cross-references
Cell line collections (Providers) ECACC; 09071501
Ximbio; 152452 - Discontinued
Anatomy/cell type resources BTO; BTO:0003258
Encyclopedic resources Wikidata; Q54881492
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number15