| Cell line name |
HCA7 colony 1 C1Y1-6 |
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| Synonyms |
C1Y1-6 |
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| Accession |
CVCL_C1KM |
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| Resource Identification Initiative |
To cite this cell line use: HCA7 colony 1 C1Y1-6 (RRID:CVCL_C1KM) |
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| Comments |
Genetic integration: Method=Transfection/transduction; Gene=RGD; 3198; Npy1r.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
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| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Glu582fs*20 (c.1742_1743insA); Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg479Ter (c.1435C>T); Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro301Glnfs*44 (c.898delC); Zygosity=Unspecified (from parent cell line).
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| Disease |
Colon adenocarcinoma (NCIt: C4349) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_2469 (HCA7 colony 1) |
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| Sex of cell |
Female |
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| Age at sampling |
58Y |
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| Category |
Cancer cell line |
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| Publications | CLPUB00715
Holliday N.D.
Functional expression of native and mutant Y1 receptors in stably transfected adenocarcinoma cell lines.
Thesis PhD (1998); University College London; London; United Kingdom PubMed=10737675; DOI=10.1139/y99-123
Holliday N.D., Pollock E.L., Tough I.R., Cox H.M.
PYY preference is a common characteristic of neuropeptide Y receptors expressed in human, rat, and mouse gastrointestinal epithelia.
Can. J. Physiol. Pharmacol. 78:126-133(2000) PubMed=12788810; DOI=10.1038/sj.bjp.0705276; PMCID=PMC1573875
Holliday N.D., Cox H.M.
Control of signalling efficacy by palmitoylation of the rat Y1 receptor.
Br. J. Pharmacol. 139:501-512(2003) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q114311566
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| Entry history |
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| Entry creation | 22-Sep-2022 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 6 |
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