ID   1BR.3.N
AC   CVCL_2282
SY   1BR3.N; 1BR.3N; 1BR.3NEO; 1BR.3neo; 1BR3neo; 1BRneo
DR   CLO; CLO_0001156
DR   CLDB; cl30
DR   ECACC; 90020508
DR   Wikidata; Q54582781
RX   PubMed=1549511;
RX   PubMed=2903889;
RX   PubMed=7519740;
RX   PubMed=11416159;
RX   PubMed=12604777;
RX   PubMed=16714754;
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
ST   Source(s): ECACC=90020508; PubMed=11416159
ST   Amelogenin: X,Y
ST   CSF1PO: 9,13
ST   D13S317: 9,12
ST   D16S539: 12,14
ST   D21S11: 30
ST   D5S818: 12
ST   D7S820: 8,10
ST   D8S1179: 12,14
ST   FGA: 21,22
ST   TH01: 9.3
ST   TPOX: 11
ST   vWA: 14,15
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2279 ! 1BR3
SX   Male
AG   23Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 16
//
RX   PubMed=1549511; DOI=10.1093/nar/20.5.991; PMCID=PMC312081;
RA   Jones C.J., Cleaver J.E., Wood R.D.;
RT   "Repair of damaged DNA by extracts from a xeroderma pigmentosum
RT   complementation group A revertant and expression of a protein absent
RT   in its parental cell line.";
RL   Nucleic Acids Res. 20:991-995(1992).
//
RX   PubMed=2903889; DOI=10.1080/09553008814552321;
RA   Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V.;
RT   "Comparative human cellular radiosensitivity: I. The effect of SV40
RT   transformation and immortalisation on the gamma-irradiation survival
RT   of skin derived fibroblasts from normal individuals and from
RT   ataxia-telangiectasia patients and heterozygotes.";
RL   Int. J. Radiat. Biol. 54:911-928(1988).
//
RX   PubMed=7519740; DOI=10.1016/0165-7992(94)90014-0;
RA   Jones C.J., Lloyd R.S., Wood R.D.;
RT   "Analysis of cells harboring a putative DNA repair gene reveals a lack
RT   of evidence for a second independent xeroderma pigmentosum group A
RT   correcting gene.";
RL   Mutat. Res. 324:159-164(1994).
//
RX   PubMed=11416159; DOI=10.1073/pnas.121616198; PMCID=PMC35459;
RA   Masters J.R.W., Thomson J.A., Daly-Burns B., Reid Y.A., Dirks W.G.,
RA   Packer P., Toji L.H., Ohno T., Tanabe H., Arlett C.F., Kelland L.R.,
RA   Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.;
RT   "Short tandem repeat profiling provides an international reference
RT   standard for human cell lines.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
//
RX   PubMed=12604777; DOI=10.1073/pnas.0437964100; PMCID=PMC151363;
RA   Dai Y., Kysela B., Hanakahi L.A., Manolis K., Riballo E., Stumm M.,
RA   Harville T.O., West S.C., Oettinger M.A., Jeggo P.A.;
RT   "Nonhomologous end joining and V(D)J recombination require an
RT   additional factor.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:2462-2467(2003).
//
RX   PubMed=16714754; DOI=10.1259/bjr/83726649;
RA   Arlett C.F., Plowman P.N., Rogers P.B., Parris C.N., Abbaszadeh F.,
RA   Green M.H.L., McMillan T.J., Bush C., Foray N., Lehmann A.R.;
RT   "Clinical and cellular ionizing radiation sensitivity in a patient
RT   with xeroderma pigmentosum.";
RL   Br. J. Radiol. 79:510-517(2006).
//