Cellosaurus U-373MG ATCC (CVCL_2219)
Cell line name | U-373MG ATCC | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | U-373MG; U373 MG; U-373-MG; U-373 MG; U373-MG; U373MG; U373; 373 MG; 373MG | ||||||||||||||||||||||||||||||||
Accession | CVCL_2219 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: U-373MG ATCC (RRID:CVCL_2219) | ||||||||||||||||||||||||||||||||
Comments | Problematic cell line: Misidentified/contaminated. Shown to be a U-251MG derivative. This cell line is not the original astrocytoma cell line established in 1973 at the University of Uppsala. See U-373MG Uppsala (Cellosaurus=CVCL_2818) for the original U-373MG cell line. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00295. Population: Caucasian. Doubling time: 40 hours (PubMed=9842975). Omics: Array-based CGH. Omics: Deep exome analysis. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872. | ||||||||||||||||||||||||||||||||
Sequence variations |
| ||||||||||||||||||||||||||||||||
Disease | Astrocytoma (NCIt: C60781) Astrocytoma (ORDO: Orphanet_94) | ||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||
Hierarchy | Parent: CVCL_0021 (U-251MG) Children:
| ||||||||||||||||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||||||||||||||||
Age at sampling | 75Y | ||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC=HTB-17; JCRB=NIHS0295; KCLB=30017; PubMed=22570425 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Web pages | https://www.atcc.org/en/support/technical-support/faqs/u-373-mg-atcc-htb-17 https://strap.nci.nih.gov/celline_detail.php?sample_id=76 http://www.nibsc.org/Default.aspx?pageid=597&id=0029&theme=default https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/u/cell-lines-detail-510.html https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx | ||||||||||||||||||||||||||||||||
Publications | PubMed=833871; DOI=10.1093/jnci/58.2.209 PubMed=450131; DOI=10.1038/279797a0 PubMed=22282976; DOI=10.1093/carcin/1.1.21 PubMed=6260907; DOI=10.1097/00005072-198105000-00001 PubMed=6220172 PubMed=6582512; DOI=10.1073/pnas.81.2.568; PMCID=PMC344720 PubMed=3518877; DOI=10.3109/07357908609038260 PubMed=2253244 PubMed=8858520; DOI=10.1007/BF00182138 PubMed=9220028; DOI=10.1016/S0303-7207(97)00080-4 PubMed=9230885; DOI=10.1093/jnci/89.14.1036 PubMed=9842975; DOI=10.1002/(SICI)1097-0215(19981218)79:6<640::AID-IJC15>3.0.CO;2-z PubMed=10074188; DOI=10.1128/JVI.73.4.3338-3350.1999; PMCID=PMC104098 PubMed=10402232; DOI=10.3892/ijo.15.2.237 PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x; PMCID=PMC8098486 PubMed=11351043; DOI=10.1038/labinvest.3780280 PubMed=11414198; DOI=10.1007/s004320000207 PubMed=14614447; DOI=10.1038/sj.onc.1207198 PubMed=14655754; DOI=10.1111/j.1750-3639.2003.tb00479.x; PMCID=PMC8095903 PubMed=16232199; DOI=10.1111/j.1349-7006.2005.00099.x; PMCID=PMC11159392 PubMed=16697959; DOI=10.1016/j.ccr.2006.03.030 PubMed=17595512; DOI=10.1159/000104150 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662 PubMed=20593219; DOI=10.1007/s11060-010-0283-9 PubMed=21406405; DOI=10.1158/0008-5472.CAN-10-3112 PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844 PubMed=26496030; DOI=10.18632/oncotarget.6171; PMCID=PMC4791243 | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Cell line collections (Providers) | ATCC; HTB-17 - Discontinued
CCLV; CCLV-RIE 0675 ECACC; 89081403 - Discontinued IZSLER; BS TCL 89 JCRB; NIHS0295 - Discontinued KCLB; 30017 NCBI_Iran; C455 | ||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0009460
CLO; CLO_0009461 CLDB; cl4587 CLDB; cl4589 CLDB; cl4964 cancercelllines; CVCL_2219 CGH-DB; 320-1 LINCS_LDP; LCL-1360 Lonza; 334 Lonza; 1006 TOKU-E; 3660 | ||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0002126 | ||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3307474
ChEMBL-Cells; CHEMBL3886101 ChEMBL-Targets; CHEMBL615024 PubChem_Cell_line; CVCL_2219 | ||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54973575 | ||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0001255 | ||||||||||||||||||||||||||||||||
Gene expression databases | GEO; GSM101681
GEO; GSM101682 GEO; GSM827314 GEO; GSM1638667 | ||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687589
Cosmic; 849849 Cosmic; 850825 Cosmic; 920819 Cosmic; 970093 Cosmic; 1066236 Cosmic; 1171226 Cosmic; 1175824 Cosmic; 1217674 Cosmic; 1294952 Cosmic; 1610742 Cosmic; 2367504 Cosmic; 2491105 Cosmic; 2701087 IARC_TP53; 2576 Progenetix; CVCL_2219 | ||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD000430
PRIDE; PXD031569 | ||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||
Last entry update | 02-May-2024 | ||||||||||||||||||||||||||||||||
Version number | 37 |