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Cellosaurus 2008/C13*5.25 (CVCL_0114)

[Text version]
Cell line name 2008/C13*5.25
Synonyms 2008/C13_5_25; 2008/c13*5.25; OV 2008/C13*5.25; OV2008/C13; 2008C13; 2008 C-13; C13; 2008/C13.R; ME180C13
Accession CVCL_0114
Resource Identification Initiative To cite this cell line use: 2008/C13*5.25 (RRID:CVCL_0114)
Comments Problematic cell line: Contaminated. Parent cell line (OV-2008) has been shown to be a ME-180 derivative (PubMed=22710073).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00522.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
Omics: Deep proteome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0473 (OV-2008)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): PubMed=22710073

Markers:
AmelogeninX
CSF1PO11
D2S133818
D3S135816
D5S81812
D7S8209
D8S117914
D13S31711,12
D16S53912,13
D18S5112
D19S43315.2
D21S1130,31
FGA23
TH018,9.3
TPOX8,10
vWA15,17

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=27561551; DOI=10.1038/ncomms12645
Coscia F., Watters K.M., Curtis M., Eckert M.A., Chiang C.Y., Tyanova S., Montag A., Lastra R.R., Lengyel E., Mann M.
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status.
Nat. Commun. 7:12645.1-12645.14(2016)

Cross-references
Cell line collections (Providers) NCBI_Iran; C446
Cell line databases/resources MCCL; MCC:0000005
cancercelllines; CVCL_0114
Anatomy/cell type resources BTO; BTO:0003989
Biological sample resources BioSample; SAMN03151842
BioSample; SAMN06481105
Chemistry resources ChEMBL-Cells; CHEMBL3308686
ChEMBL-Targets; CHEMBL614863
PubChem_Cell_line; CVCL_0114
Encyclopedic resources Wikidata; Q54583043
Gene expression databases GEO; GSM711717
GEO; GSM851911
Polymorphism and mutation databases Cosmic; 948294
Cosmic; 1479983
Proteomic databases PRIDE; PXD003668
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number29