ID   2008/C13*5.25
AC   CVCL_0114
SY   2008/C13_5_25; 2008/c13*5.25; OV 2008/C13*5.25; OV2008/C13; 2008C13; 2008 C-13; C13; 2008/C13.R; ME180C13
DR   BTO; BTO:0003989
DR   MCCL; MCC:0000005
DR   BioSample; SAMN03151842
DR   BioSample; SAMN06481105
DR   ChEMBL-Cells; CHEMBL3308686
DR   ChEMBL-Targets; CHEMBL614863
DR   Cosmic; 948294
DR   Cosmic; 1479983
DR   GEO; GSM711717
DR   GEO; GSM851911
DR   NCBI_Iran; C446
DR   PRIDE; PXD003668
DR   PubChem_Cell_line; CVCL_0114
DR   Wikidata; Q54583043
RX   PubMed=22710073;
RX   PubMed=27561551;
CC   Problematic cell line: Contaminated. Parent cell line (OV-2008) has been shown to be a ME-180 derivative (PubMed=22710073).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00522.
CC   Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 45240; Human papillomavirus type 68 (HPV68).
CC   Omics: Deep proteome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from metastatic site: Omentum.
ST   Source(s): PubMed=22710073
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 12,13
ST   D18S51: 12
ST   D19S433: 15.2
ST   D21S11: 30,31
ST   D2S1338: 18
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 9
ST   D8S1179: 14
ST   FGA: 23
ST   TH01: 8,9.3
ST   TPOX: 8,10
ST   vWA: 15,17
DI   NCIt; C27676; Human papillomavirus-related cervical squamous cell carcinoma
DI   ORDO; Orphanet_213767; Squamous cell carcinoma of the cervix uteri
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0473 ! OV-2008
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 21-03-23; Version: 27
RX   PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017;
RA   Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K.,
RA   Lessey B.A., Jordan V.C., Bradford A.P.;
RT   "DNA profiling analysis of endometrial and ovarian cell lines reveals
RT   misidentification, redundancy and contamination.";
RL   Gynecol. Oncol. 127:241-248(2012).
RX   PubMed=27561551; DOI=10.1038/ncomms12645;
RA   Coscia F., Watters K.M., Curtis M., Eckert M.A., Chiang C.Y.,
RA   Tyanova S., Montag A., Lastra R.R., Lengyel E., Mann M.;
RT   "Integrative proteomic profiling of ovarian cancer cell lines reveals
RT   precursor cell associated proteins and functional status.";
RL   Nat. Commun. 7:12645.1-12645.14(2016).