| Description |
A hypodiploid cell line from mammary gland; breast; primary ductal carcinoma, held at ATCC, included in Cancer Genome Project at the Sanger Institute. |
| Notable Features |
Hypodiploid, extremely rearranged with 17 structural chromosome abnormalities. No normal chromosomes 1, 8, 11, X. Losses involve X, 2q, 4, 8, 13, 14, 15, 17. |
| Representative SKY Karyotype |  |
|
38(35-39) X, -X, der(X)t(X;5;1), der(1)t(X;1), der(1)del(1)(p21-pter), 2x1, der(2)t(2;20), 3x1, t(3;17), 4x1, der(4)t(4;8)a, 5x1, t(5;8;20), 6x1, der(6)t(6;17)(), 7x1, der(7)t(7;15)( p15?;?), der(8)t(5;8)(?;p21?), 9x1, der(9)t(8;9)(?;p21?), 10x1, der(10)t(3;10), der(11)t(10;11;6), der(11)t(11;12)dup(12), 12x1, 13x1, 14x1, i(14q) a, 15x1, 16x2, 17x1, 18x2, 19x2, 20x1, der(20)t(11;20), 21x2, 22x1, der(22)t(8;22)(q12;?) a in less than 50% of the cells |
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