| Description |
A hypertriploid cell line from mammary gland, breast, primary ductal carcinoma, held at the ATCC, included in the Cancer Genome Project at the Sanger institute. |
| Notable Features |
Hypertriploid, with 24 structural chromosome rearrangements, some cells with dmin, all cells have long hsrs involving chromosomes 8, 11, 20. Losses involve chromosomes X, 17, 18; gains involve 3, 4, 5p, 6, 8, 9, 11hsr, 12, 19, 20hsr, 21, 22. |
| Representative SKY Karyotype |  |
|
74(66-79), XX, 1x2, der(1)t(1;20), der(1)t(1;16), der(1)t(1;8;4;11;9?), 2x1, der(2)t(2;3), der(2)t(2;3?;5)dup(2), 3x2, der(3)t(3;2;3;13), der(3)del(3), 4x3, der(4)del(4)t(4;11;13), 5x3, der(5)del(5)(q10-qter), i(5p)?, del(5)t(5;11), 6x4, 7x2, der(7)del(7)t(7;16), der(7)t(7;11), der(7)del(7), 8x2, der(8)t(8;11)hsr8qx2, 9x1, der(9?)t(9;11), 10x3, 11x1, der(11)t(9;11), der(11?)t(9;11;20;9)hsr11;hsr20, 12x4, 13x2, der(13)t(5;13)(?;q14-q21), 14x1, der(11;14)(p10-q10)x2, 15x2, 16x2, der(16)t(10;16), der(17)t(4;17), der(17)t(17;4;17;15), 18x2, 19x4, 20x1, der(20)t(7;20), 21x4, 22x4 |
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