| Description |
A near-tetraploid cell line from mammary gland; breast; duct; primary ductal carcinoma, held at ATCC, included in the Cancer Genome Project at the Sanger Institute. |
| Notable Features |
A hypo-tetraploid cell line, extremely rearranged, with 48 structural chromosome abnormalities, all cells contain dmin involving chromosomes 1, 3, 11, 13 and hsrs involving chromosomes 21, 3, 19. |
| Representative SKY Karyotype |  |
|
80(74-82), -X, der(X)t(10;X;12), der(X)t(X;1), 1x1, der(1)t(1;5), der(1)t(1;10?), i(2q), t(2;15), t(2;6;9;X), t(2;20), 2x2, del(3)x2, i(4p), der(4)t(4;22)(q10;q10)x2, isoder(4;18), 5x4, der(6)t(1;6)(?p11-p12, t(6;11), der(7)t(7p;17)x2, der(7)t(7q;X;7;17), der(7)t(7;11;10), 8x1, der(6;8)(q10;q10), del(8)(p10-pter)x2, t(8;1), t(8;20), 9x1, der(4;9)(p10;q10), der(7;9)(p10;q10), 10x1, del(10), der(10)t(5;10)x2, 11x1, der(11)t(3;11), der(?)(18;11;1), der(11?)t(5;11;1;3), 12x3, 13x1, der(13)t(2;13)(?;p11), der(8;14)(p10;q10)x2, der(14)t(10;14), der(14;22)(q10;q10), 15x1, t(15;19), t(?;15;1), t(15;?), 16x2, der(16)t(16;20), 17x2, der(17?)t(1;17), der(17?)t(6;17), 18x1, der(18?)t(18;22), der(18?)t(15;18), der(?)t(18;5/6?), 19x2, der(19)t(19;1;10), 20x3, der(20)t(20;9;20), 21x1, der(21)t(8;21)?, der(21)t(21;3;X)hsr(21;3), der(22)t(19;22)hsr(19), der(22)t(18;22) a
a in less than 50% of the cells |
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