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Cellosaurus EFC-2 (CVCL_ZV49)

[Text version]
Cell line name EFC-2
Accession CVCL_ZV49
Resource Identification Initiative To cite this cell line use: EFC-2 (RRID:CVCL_ZV49)
Comments Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2964515; DOI=10.1007/BF00148389
Yung W.-K.A., Steck P.A., Kelleher P.J., Moser R.P., Rosenblum M.G.
Growth inhibitory effect of recombinant alpha and beta interferon on human glioma cells.
J. Neurooncol. 5:323-330(1987)

PubMed=9070656; DOI=10.1038/sj.onc.1200925
Ligon A.H., Pershouse M.A., Jasser S.A., Yung W.-K.A., Steck P.A.
Identification of a novel gene product, RIG, that is down-regulated in human glioblastoma.
Oncogene 14:1075-1081(1997)

PubMed=9090379; DOI=10.1038/ng0497-356
Steck P.A., Pershouse M.A., Jasser S.A., Yung W.-K.A., Lin H., Ligon A.H., Langford L.A., Baumgard M.L., Hattier T., Davis T., Frye C., Hu R., Swedlund B., Teng D.H.-F., Tavtigian S.V.
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.
Nat. Genet. 15:356-362(1997)

PubMed=9230885; DOI=10.1093/jnci/89.14.1036
Gomez-Manzano C., Fueyo J., Kyritsis A.P., McDonnell T.J., Steck P.A., Levin V.A., Yung W.-K.A.
Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis.
J. Natl. Cancer Inst. 89:1036-1044(1997)

Cross-references
Encyclopedic resources Wikidata; Q98125951
Polymorphism and mutation databases IARC_TP53; 22882
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7