Cellosaurus cell line 161MA-M (CVCL

Cross-references
Cell line name	161MA-M
Synonyms	161 MAnchester-M
Accession	CVCL_ZT85
Resource Identification Initiative	To cite this cell line use: 161MA-M (RRID:CVCL_ZT85)
Comments	Population: Indian. Derived from site: Metastatic; Retroperitoneal space; UBERON=UBERON_0003693.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu344Pro (c.1031T>C); ClinVar=VCV000012375; Zygosity=Heterozygous (PubMed=8649785).
Disease	Li-Fraumeni syndrome (NCIt: C3476) Retroperitoneal leiomyosarcoma (NCIt: C27904) Li-Fraumeni syndrome (ORDO: Orphanet_524) Leiomyosarcoma (ORDO: Orphanet_64720)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_ZT83 ! 160MA CVCL_ZT84 ! 161MA-F
Sex of cell	Male
Age at sampling	45Y
Category	Finite cell line
Publications	PubMed=8649785 Varley J.M., McGown G., Thorncroft M., Cochrane S., Morrison P., Woll P.J., Kelsey A.M., Mitchell E.L.D., Boyle J., Birch J.M., Evans D.G.R. A previously undescribed mutation within the tetramerisation domain of TP53 in a family with Li-Fraumeni syndrome. Oncogene 12:2437-2442(1996)
Encyclopedic resources	Wikidata; Q98125287
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	7