Cellosaurus cell line 161MA-F (CVCL

Cross-references
Cell line name	161MA-F
Synonyms	161 MAnchester-F
Accession	CVCL_ZT84
Resource Identification Initiative	To cite this cell line use: 161MA-F (RRID:CVCL_ZT84)
Comments	Population: Indian. Senescence: Senesces at 19 PDL (PubMed=9649131). Derived from site: In situ; Mesentery; UBERON=UBERON_0002095.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu344Pro (c.1031T>C); ClinVar=VCV000012375; Zygosity=Hemizygous (PubMed=8649785; PubMed=9649131).
Disease	Li-Fraumeni syndrome (NCIt: C3476) Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_ZT83 ! 160MA CVCL_ZT85 ! 161MA-M
Sex of cell	Male
Age at sampling	45Y
Category	Finite cell line
Publications	PubMed=8649785 Varley J.M., McGown G., Thorncroft M., Cochrane S., Morrison P., Woll P.J., Kelsey A.M., Mitchell E.L.D., Boyle J., Birch J.M., Evans D.G.R. A previously undescribed mutation within the tetramerisation domain of TP53 in a family with Li-Fraumeni syndrome. Oncogene 12:2437-2442(1996) PubMed=9649131; DOI=10.1038/bjc.1998.364; PMCID=PMC2150396 Boyle J.M., Mitchell E.L.D., Greaves M.J., Roberts S.A., Tricker K., Burt E., Varley J.M., Birch J.M., Scott D. Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families. Br. J. Cancer 77:2181-2192(1998)
Encyclopedic resources	Wikidata; Q98125286
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	7