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Cellosaurus LanthaScreen STAT5 (JAK2 V617F) U2OS (CVCL_ZJ10)

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Cell line name LanthaScreen STAT5 (JAK2 V617F) U2OS
Accession CVCL_ZJ10
Resource Identification Initiative To cite this cell line use: LanthaScreen STAT5 (JAK2 V617F) U2OS (RRID:CVCL_ZJ10)
Comments Population: Caucasian.
Characteristics: Transfected with both a EmGFP-STAT5A and a GST-JAK2(V617F) constructs whose expression are under the control of a CMV promoter.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6192; JAK2 (Note=With p.Val617Phe).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11366; STAT5A.
Genetic integration: Method=Transfection/transduction; Gene=FPbase; GLAD6; Emerald (Note=EmGFP, green fluorescent protein derived from GFP).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Web pages https://www.thermofisher.com/order/catalog/product/K1588
Cross-references
Encyclopedic resources Wikidata; Q98126860
Entry history
Entry creation02-Jul-2020
Last entry update10-Sep-2024
Version number7