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Cellosaurus MOC2LN (CVCL_ZD38)

[Text version]
Cell line name MOC2LN
Accession CVCL_ZD38
Resource Identification Initiative To cite this cell line use: MOC2LN (RRID:CVCL_ZD38)
Comments Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; MGI; MGI:96680; Kras; Simple; p.Gln61His (c.183A>T); Zygosity=Unspecified (from autologous cell line MOC2).
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Glu225Ter; Zygosity=Unspecified (from autologous cell line MOC2).
Disease Squamous cell carcinoma of the mouse oral cavity (NCIt: C23049)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 Cxcr3-/-.
Originate from same individual CVCL_ZD33 ! MOC2
Sex of cell Female
Category Cancer cell line
Publications

PubMed=24668645; DOI=10.1158/1078-0432.CCR-14-0205
Onken M.D., Winkler A.E., Kanchi K.-L., Chalivendra V., Law J.H., Rickert C.G., Kallogjeri D., Judd N.P., Dunn G.P., Piccirillo J.F., Lewis J.S. Jr., Mardis E.R., Uppaluri R.
A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.
Clin. Cancer Res. 20:2873-2884(2014)

PubMed=25729643; DOI=10.1016/j.gdata.2014.11.006
Chalivendra V., Kanchi K.-L., Onken M.D., Winkler A.E., Mardis E.R., Uppaluri R.
Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer.
Genomics Data 3:61-62(2015)

Cross-references
Encyclopedic resources Wikidata; Q98127277
Gene expression databases GEO; GSM1213097
GEO; GSM1213098
GEO; GSM1213099
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number6