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Cellosaurus BmN4 (CVCL_Z634)

[Text version]
Cell line name BmN4
Synonyms BmN-4; BM-N4
Accession CVCL_Z634
Resource Identification Initiative To cite this cell line use: BmN4 (RRID:CVCL_Z634)
Comments Group: Insect cell line.
Virology: Infected by Bombyx mori macula-like latent virus (BmMLV).
Doubling time: 73.3 hours (PubMed=24934233); 58 +- 6 hours (Note=In static culture), 72 +- 2 hours (Note=In suspension culture) (PubMed=10585188).
Omics: Deep proteome analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Bombyx mori (Silk moth) (NCBI Taxonomy: 7091)
Hierarchy Parent: CVCL_Z633 (BM-N)
CVCL_Z635 (BmN-SFM)CVCL_Z089 (BmN4-DR)CVCL_Z090 (BmN4-IR)
CVCL_Z091 (BmN4-SID1)
Sex of cell Female
Category Spontaneously immortalized cell line

Yanase T., Yasunaga C., Kawarabata T.
Replication of Spodoptera exigua nucleopolyhedrovirus in permissive and non-permissive lepidopteran cell lines.
Acta Virol. 42:293-298(1998)

PubMed=10585188; DOI=10.1021/bp990119f
Keith M.B., Farrell P.J., Iatrou K., Behie L.A.
Screening of transformed insect cell lines for recombinant protein production.
Biotechnol. Prog. 15:1046-1052(1999)

PubMed=15827172; DOI=10.1128/JVI.79.9.5577-5584.2005
Katsuma S., Tanaka S., Omuro N., Takabuchi L., Daimon T., Imanishi S., Yamashita S., Iwanaga M., Mita K., Maeda S., Kobayashi M., Shimada T.
Novel macula-like virus identified in Bombyx mori cultured cells.
J. Virol. 79:5577-5584(2005)

PubMed=16756546; DOI=10.1111/j.1365-2583.2006.00639.x
Taniai K., Lee J.-H., Lee I.-H.
Bombyx mori cell line as a model of immune-system organs.
Insect Mol. Biol. 15:269-279(2006)

PubMed=22714272; DOI=10.1007/s10529-012-0971-y
Lee J.M., Kawakami N., Mon H., Mitsunobu H., Iiyama K., Ninaki S., Maenaka K., Park E.Y., Kusakabe T.
Establishment of a Bombyx mori nucleopolyhedrovirus (BmNPV) hyper-sensitive cell line from the silkworm e21 strain.
Biotechnol. Lett. 34:1773-1779(2012)

PubMed=24934233; DOI=10.1007/s11626-014-9781-y
Iwanaga M., Adachi Y., Uchiyama K., Tsukui K., Katsuma S., Kawasaki H.
Long-term adaptation of the Bombyx mori BmN4 cell line to grow in serum-free culture.
In Vitro Cell. Dev. Biol. Anim. 50:792-796(2014)

PubMed=33023468; DOI=10.1186/s12864-020-07088-7
Levin M., Scheibe M., Butter F.
Proteotranscriptomics assisted gene annotation and spatial proteomics of Bombyx mori BmN4 cell line.
BMC Genomics 21:690.1-690.14(2020)

Cell line collections (Providers) NISES; SK0023
Cell line databases/resources ICLDB; bmn4
Anatomy/cell type resources BTO; BTO:0005690
Encyclopedic resources Wikidata; Q54797601
Entry history
Entry creation10-Apr-2015
Last entry update29-Jun-2023
Version number12